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A New IBS Solution: Bacteria-The Missing Link in Treating Irritable Bowel Syndrome
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About the Author
Dr. Mark Pimentel was born in Thunder Bay, Ontario, Canada. He obtained his medical degree at the University of Manitoba in Winnipeg, Canada. He did his residency in Internal Medicine at the University of Manitoba as well. He is now assistant Professor of Medicine at the UCLA Geffen School of Medicine and is the Director of the Gastrointestinal Motility Program at Cedars-Sinai Medical Center.
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Product details
Paperback: 156 pages
Publisher: Health Point Press; First Printing edition (May 15, 2006)
Language: English
ISBN-10: 0977435601
ISBN-13: 978-0977435609
Product Dimensions:
6.1 x 0.5 x 9.1 inches
Shipping Weight: 9.6 ounces
Average Customer Review:
4.5 out of 5 stars
124 customer reviews
Amazon Best Sellers Rank:
#88,973 in Books (See Top 100 in Books)
This one is a very comprehensive book on IBS/SIBO. It really helps to piece together various pieces of the puzzle for someone who's been bothered by an "IBS" of sorts.I myself am more on the constipation side of things with occasional manifestations of extra flatulance, gurgling stomach etc. (but not anything like frequent diarrhea or severe bloating). I'm definitely sensitive to fast carbs like white bread and sugar packed stuff like candies and chocolate. I'm actually less sensitive to pastas and also sourdough or non-yeast bread. I've tested for pretty much everything already without much results though. For one, it's not celiac disease. It's also not gluten intolerance per se (I've done genetic testing for that). It's not parasites. I also don't have much "inflammation" or anything like autoimmune effects according to a variety of blood tests. I do have some issues with gut flora according to stool tests, and I might have a lower than necessary stomach acid, though (currently awaiting for the latest test results). I might have some lactose intolerance because of my gut flora issues (basically, it's an excess of E.coli lactose negative). I do have iron, B12 and some folic deficiencies. Supplementing with B vitamins and iron does help with the deficiency, but as soon as I stop, it's back again. I've been taking various probiotics with no long-term effects - as soon as I stop, it's all back in a day or two. I've got a stressful life balancing various family stuff and a rapidly developing international startup. I developed some annoying side-effects to all of the above that really affect my quality of life. As a result, I've been also supplementing with diosmin and stone root, on a permanent basis - to keep the side-effects under control. What's even more annoying is that laxatives actually make it worse (it's a well-known fact, btw, but still annoying). I've switched to Natural Calm magnesium lately, and it appears to be much better than anything else for consistent bowel movements, though. I've been also taking Trimebutine (200mg, 3 times a day with meals) and it really made a difference at the beginning, but now it's much less pronounced, though definitely helps a lot (especially with bread and pasta).Now about the book.PROS. After studying various materials for almost 2 years now, I tend to conclude this book is the most detailed story behind IBS/SIBO connection so far. If you've been checking books like "Breaking the Vicious Cycle", "Fiber Menace", "The Good Gut", "The Microbiome Diet", "Why Stomach Acid Is Good for You", and maybe also various "SCD lifestyle" and "FODMAPs" resources on the Web, this book is the very necessary addition to your library. It kinda summarizes everything in a consistent and easy to digest manner, and gives you further direction if you're still stumped. I'd really recommend checking out more books on every particular topic, though (e.g. on stomach acid). What I also liked about this book is that it's got an entire section on "alternative approaches" to mitigate the IBS effects. I can confirm that mindful meditation does help to alleviate the "IBS symptoms" if practiced on a consistent basis - basically, if done every day. There are many great apps already for that, Headspace being particularly useful to me personally.CONS. It appears the book is already quite outdated. E.g., Zelnorm/Tegaserod appears to be withdrawn from the market since 2007. Still the book sort of advertises it. The book also doesn't mention relatively benign but very effective spasmolytics like Trimebutine (possibly because it's not approved pretty much everywhere but not in the U.S.?). In fact, the book says spasmolytics don't help - but that's probably in regards to two particular medicines mentioned in the text. The antibiotics approach is certainly something worth considering after all the comprehensive tests are done and severe bacterial infection confirmed, however it's more like an atomic bomb to your gut. There are things like bacteriophages that have been used in certain countries for almost a century now as a great alternative to antibiotics..*** Update ***Still can't fully deal with my "IBS", though :) Preferred not to go the "anti-biotics" path. Been trying various probiotics, with varying results. Been changing my diet too, with mixed results (no panacea from any combination I've tried so far). Also tried a bunch of esoteric (supplement) things. One interesting fact that I've discovered recently — Luna by Nested Naturals helps to improve my bowel movements quite significantly. For the mildest laxative (and most useful so far) I'd recommend trying out "KAL - Magnesium Glycinate 400".
I spent thousands of dollars with several functional, integrative doctors specialized in without any results . But my symptoms started to improve since I read and follow this book. the most important advise from this book is improving the Migrating Motor complex- MMC
At first I thought everything Dr. Pimentel writes about in this book made sense--and on some levels still does. I liked his theory on IBS being caused by small intestinal bacterial overgrowth (SIBO). However, this certainly is not always the case. I figured out my IBS issues were a combination of SIBO, slow gut motility, inability to digest fiber (it literally tears up my intestines), microscopic colitis, and bile acid malabsorption. I did like his diet and food suggestions. I gave three stars as I have a serious issue with Dr. Pimentel's hard sell in this book for the antibiotic Xifaxan. This bothers me as it well documented that he receives money from the drug's maker--Salix Pharmaceuticals. I have a serious problem with doctors who are shills for pharmaceutical companies. It creates a dangerous bias. Also, I saw an infectious disease doctor who told me GI and primary doctors should not be prescribing this drug the way they do--that it disrupts the microflora even further and is a potent antibiotic.
Reading this book was like reading about all my health problems. The Doctor covers how IBS, Fibromyalgia, and intercyctial cysiitis are realated. I have all 3 of these conditions, so this book was extremely helpful to me. The cause being SIBO
I like Dr. Pimentel's book. However, I think his focus on bacteria to be a little excessive, when repeated studies can't seem to confirm a particular microbial source. He touches on the idea of toxins relating to IBS (e.g. exotoxin A, LPS, etc...). However, after much research and curing my own IBS I believe IBS is primarily caused by microbial toxins. These toxins bind to toll like receptors on the immune system triggering systemic inflammation. The inflammation of the intestinal tract triggers the symptoms of pain and digestive issues. It also reduces motility of the villi of the intestinal wall. This reduced motility allows bacteria to set up in the mucosal layer and form biofilms. This leads to the SIBO that Dr. Pimentel talks about. Accordingly, his procedure does not talk enough about toxin avoidance and treating for toxins after infection. Since IBS often appears after infection, there is probably a high likelihood that the toxins from the infection are playing a role in the IBS. Toxins can also come from the air, water or food that we breathe, drink or eat. So one needs to be aware of indoor air quality (mold), tap water (algal toxins such as microcystin) and food (vomitoxin in wheat) and of course any toxins associated with infection.
I had been seriously ill for 9 months when I happened upon this book while doing some research about my digestive problems. I had been going to doctors for months and making no progress.This book really put the pieces together and we finally were able to figure out what was wrong with me and get me back on the right track. I highly recommend it for anyone with an IBS diagnosis, particularly if their digestive problems seem to have started with food poisoning or other illness.
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